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CL3 Biosafety containment level 3 (See #16 2) Rad Basic between 1 EQ and 5ALI Rad Intermediate between 5ALI and 50 ALI (See #16 3) Rad High between 50 ALI and 500 ALI (See #16 3) OHSA Sec 25(2)(h)/University of Toronto requirement/ PHAC CL1 Guidelines Radiation CNSC GD-52 - Design Guide for Nuclear Substance Laboratories and Nuclear
Operations at Biosafety Level III: The P3 Laboratory Yoshio Ichinose Shingo Inoue Masaaki Shimada Gabriel Miring'u Betty Muriithi Angela Makumi Ernest Wandera Martin Bundi Chika Narita Salame Ashur Allan Kwalla Amina Galata Erick Odoyo Sora Huqa Mohammed Shah Mohammed Karama Masahiro Horio 1 Introduction Biomedical research on pathogenic agents has steadily grown
Biosafety Levels and Agents of Disease August 1 2013 Acharya Tankeshwar Microbiology for Beginners 0 Biosafety level designations are based on a composite of the design features construction containment facilities equipment practices and operational procedures required for working with agents from the various risk groups
Basic Laboratory Design for Biosafety Level 3 Containment facilities are described in the CDC/NIH publication Biosafety in Microbiological and Biomedical Laboratories (BMBL) and in the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines) BSL-3 Laboratory Facilities The laboratory must be separated from areas that are open to unrestricted
Chapter 22 - Design Considerations for New Containment Zones The principal objective of containment zone design is to provide an environment where pathogens and toxins can be safely handled and stored Given the wide range of pathogens toxins and sample types that may be handled in a containment zone and the variety of work that may take place (e g laboratory manipulation work with
Biosafety Level 2 (BSL-2) is for organisms with moderate hazard to humans such as influenza and legionella Facilities and engineering safeguards should resemble a medical diagnostic laboratory Biosafety Level 3 (BSL-3) is for disease-causing organisms that can cause death in humans Examples include tuberculosis and West Nile virus Such
Laboratory biosafety manual 19 3 rd ed Geneva: World Health Organization 2004 20 Le Due JW Anderson K Bloom ME Estep JE Feldmann H Geisbert JB et al Framework for leadership and training of biosafety level 4 laboratory workers Emerg Infect Dis 2008 14: 1685-8 21 Kaiser J Biosafety breaches Accidents spur a closer look at
The Biosafety Level 3 laboratory is significantly more advanced than the BSL-2 lab in terms of its design infrastructure and operational procedures and practices These labs incorporate a variety of primary containment equipment which may include Class III BSCs for handling materials with a high or unknown risk level From a facility-engineering standpoint another critical aspect are the
Laboratory facilities are designated as basic – Biosafety Level 1 basic – Biosafety Level 2 containment – Biosafety Level 3 and maximum containment – Biosafety Level 4 Biosafety level designations are based on a composite of the design features construction containment facilities equipment practices and operational procedures
The Biosafety Officer (in collaboration with the Institutional Biosafety Committee) must approve the location and design of any BSL-3 facility and has final authority to authorize the commencement of BSL-3 work The Biosafety Level-3 facility design and operational procedures must be documented The facility must be tested for verification that the design and operational
Initial Biosafety Training provides initial training for researchers handling biohazards in a research or clinical laboratory The course addresses awareness of biohazards risk assessment and key risk management principles including work practices personal protective equipment (PPE) engineering controls and emergency response
C Basic Laboratory Design for Biosafety Levels 1 and 2 Laboratories 7-2 D Basic Laboratory Design for Biosafety Level 3 Laboratories 7-5 Appendix 7-1 BMBL Requirements 7-20 Appendix 7-2 Biological Safety Cabinets 7-23 8 ADDITIONAL REQUIREMENTS FOR RADIOACTIVE MATERIAL LABORATORIES 8-1 A Scope 8-1 B Basic Laboratory Design 8-1 C Ventilation
Biosafety Level 3 laboratory is designed and provided for work with microorganisms in Risk Group 3 or with large volumes of microorganisms in Risk Group 2 which might lead to aerosol spread In addition to the practices of Biosafety Level 1 2 BSL-3 enhances the protection measures and safety programmes of BSL-1 2 The differences in the
Laboratory Design Guidelines 2013 Design Guidelines 3 | Page I INTRODUCTION Purpose: UNC-Chapel Hill has a continuing need to modernize and upgrade its facilities The resulting construction projects often have significant health and safety requirements due to regulatory oversight Since
Ergonomics Design and Laboratory Spaces Electrical Safety and Power Systems Lab Ventilation and Fume Hoods Emergency Equipment Pressure Vessel Components and Systems and Compressed Gas Cylinders Hazardous Material Storage and Use Areas Biosafety Introduction Scope Design Guide for BSL 1-2 Design Guide for BSL 3 Basic Laboratory
The biosafety professional may be called upon to participate in the planning design and validation of a new biocontainment laboratory or renovation of an existing facility The biosafety professional's training and experience is usually limited to the sciences and they often lack the knowledge of basic engineering principles This course is intended to fill the gap by providing basic
Basic Biosafety Training (BIO303) Course Material Basic Biosafety Training (BIO303) Course Material Page 3 Last Updated: 05/29/2019 Training technical skills and willingness to develop good work habits are critical in determining the relative risk for a specific lab Facility safeguards and proper care and maintenance of containment equipment are
C Basic Laboratory Design for Biosafety Levels 1 and 2 Laboratories 7-2 D Basic Laboratory Design for Biosafety Level 3 Laboratories 7-5 Appendix 7-1 BMBL Requirements 7-20 Appendix 7-2 Biological Safety Cabinets 7-23 8 ADDITIONAL REQUIREMENTS FOR RADIOACTIVE MATERIAL LABORATORIES 8-1 A Scope 8-1 B Basic Laboratory Design 8-1 C Ventilation
Each laboratory conducting Biosafety Level 3 work must have written laboratory-specific biosafety practices and procedures approved by the IBC prior to commencement of work It must be reviewed yearly and updated with any change in protocol or procedure Practices and procedures set forth here are to be adopted into the laboratory-specific
facilities as basic – Biosafety Level 1 basic – Biosafety Level 2 containment – Biosafety Level 3 and maximum containment – Biosafety Level 4 Table 1 describes the risk groups Table 2 relates them to the laboratory designations and Table 3 summarizes the requirements at the four biosafety levels Table 1
They follow basic safety procedures called Standard Microbiological Practices and require no special equipment or design features Standard engineering controls in BSL-1 laboratories include easily cleaned surfaces that are able to withstand the basic chemicals used in the laboratory Biosafety Level
To meet this goal the IBC imposes requirements for safe laboratory and biological safety practices reviews and approves policies procedures training programs and facilities pursuant to the safe use of biological agents other biological materials and toxins Biosafety level designations are based on a composite of the design features construction containment facilities equipment
The new Rutgers Regional Biocontainment Laboratory (Rutgers RBL) is a self-contained 40 000 sq ft facility that serves as one of thirteen national centers designated by the National Institutes of Health (NIH) for research on biosafety level 3 (BSL3) infectious agents Adjoining the BSL3 vivarium and BSL3 laboratories at the International Center for Public Health (ICPH) the total BSL3
The Biosafety Level-3 (BSL-3) Core Facility established in November 2014 at the NUS Yong Loo Lin School of Medicine (NUS Medicine) is the largest research-focused biocontainment facility in Singapore The facility supports research and diagnostic work involving a range of RG3 biological agents It is certified by the Biosafety Branch of the Singapore Ministry of Health and the Animal
Working at Biosafety Level 3 (BSL-3) BSL-3 laboratory facilities ensure safe working conditions for researchers carrying out studies requiring stringent levels of biological containment Work with agents or materials at BSL-3 requires registration approvals and training beyond that required for other basic research at Penn as set forth by federal regulations CDC/NIH guidelines and Penn
1 2 How to use the Laboratory Biosafety Manual 3 SECTION 2: Risk assessment 4 2 1 Gather information 8 2 2 Evaluate the risks 10 2 3 Develop a risk strategy 15 2 4 Select and implement control measures 16 2 5 Review risks and control measures 23 SECTION 3: Core requirements 25 3 1 Good microbiological practices and procedures 25 3 2 Personnel competence and training 29 3 3 Facility design 30 3
WUSM FMD Design Standards Section 2 02 "Basic Laboratory Design Features" to be revised to only include BSL-1 and BSL-2 design features 2 03 – BSL3 Design Guidelines Introduction and Basis of Design: The following BSL-3 Design Guidelines are intended to assist the Washington University School of Medicine (WUSM) and its stakeholders with programming and design of new Biosafety Level 3
biohazard posed by the agents used and for the laboratory activity Biosafety Level 1 Practices safety equipment and facilities appropriate for work with defined and characterized strains of viable micro organisms not known to cause disease in healthy adult humans The laboratory is not necessarily separated from the general traffic patterns in the building Work is generally conducted on
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